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Here’s how ‘singing’ mice belt out their tiny tunes

Дата публикации: 08-07-2026 10:30:00

Balloon-like air sacs in the mice's throats create whistling songs. No other animal is known to make calls in this way.

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Disney’s Cinderella is not the only place you can hear mice “sing.” Some real-world rodents also serenade each other. And now, scientists know how. The mice inflate tiny, balloon-like sacs in their airways. This creates whistling tunes.

Making music this way may be unique in the animal kingdom.

The critters are known as Alston’s singing mice. Found in the forests of Mexico and Central America, they truly live up to their name. Both males and females communicate with trains of high-pitched notes. Remarkably, their songs are more complex than those of any other rodent.

In just a 10-second song, an Alston’s singing mouse belts out around 100 individual breaths and notes. The melody attracts mates and warns rival males to stay away, says Samantha Smith. The song’s speed and length make it far more “extreme” than other rodents’ calls, she adds. Smith is a biologist at the University of Lausanne. That’s in Switzerland.

Smith is part of a team that wanted to know how the vocal systems of Alston’s singing mice evolved to create melodies. They started by dissecting the larynges of deceased animals. This “voice box” is a part of their bodies that helps mice (and us) breathe, swallow and make sound.

Watch one Alston’s singing mouse serenade the sky with its complex song.

The researchers hooked each excised mouse voice box to a tube. Then, they pointed a microphone and camera toward its top. “A [voice box] is basically just a tube with a valve in it that can open and close,” explains Smith. To see how the voice box moved and produced sound, the team blew air through the tube.

Sometimes, the voice box produced sounds that ranged in the mouse’s natural pitch. But this happened only when a pouch on the inside of the voice box was inflated. When the researchers blocked this balloon with bits of wax or small metal balls, the voice box went silent. Cutting the sac had the same effect. The air sac, it seemed, is key to making the songs.

Other rodents have air sacs, but they don’t appear to use them to sing.

Smith and her teammates shared their findings May 6 in Proceedings of the Royal Society B.

A unique musical talent

Raffaela Lesch is impressed by the team’s experiment and its choice of species. She works at the University of Arkansas at Little Rock. As a bioacoustician, she studies how animals use sound to communicate.

“Working with [voice boxes] this small is not an easy task,” she says. But for Lesch, learning more about how rodents produce sound is exciting. They’re “such a diverse group with such fascinating social, behavioral and ecological adaptions,” she says. 

It’s not yet clear how the sac generates its whistle. The sound could come from air vibrating at the sac’s entrance. That would be similar to the way opening a car’s sunroof can make noise as air rushes past the opening.

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Another possibility is a bit like how flutes and organ pipes work. A sharp cartilage rim at the sac’s entrance may be deflecting air, producing the tone.

Inflatable sacs in airways have evolved multiple times. Primates, birds, reptiles, frogs and other animals have them. But in those cases, air sacs alter or amplify sound produced elsewhere in the respiratory tract. (That’s the system of organs that are involved in breathing.) The songs of the singing mice, on the other hand, are made by the sacs themselves.

“Our study expands our understanding of the ways in which [air sacs] can shape vocal communication,” Smith says. Studying different features of rodent air sacs may help reveal how these songs first evolved — no Disney magic needed.

Power Words More About Power Words

amplify: To increase in number, volume or other measure of responsiveness.

biologist: A scientist involved in the study of living things.

birds: Warm-blooded dinosaurs with wings that first showed up at least 150 million years ago. Birds are jacketed in feathers and produce young from the eggs they deposit in some sort of nest. Most birds fly, but throughout history there have been the occasional species that don’t.

cartilage: (adj. cartilaginous) A type of strong connective tissue often found in joints, the nose and ear. In certain primitive fishes, such as sharks and rays, cartilage provides an internal structure — or skeleton — for their bodies.

colleague: Someone who works with another; a co-worker or team member.

deceased: An adjective that describes someone who has died.

ecological: An adjective that refers to a branch of biology that deals with the relations of organisms to one another and to their physical surroundings. A scientist who works in this field is called an ecologist.

organ: (in biology) Various parts of an organism that perform one or more particular functions. For instance, an ovary is an organ that makes eggs, the brain is an organ that makes sense of nerve signals and a plant’s roots are organs that take in nutrients and moisture.

pitch: (in acoustics) The word musicians use for sound frequency. It describes how high or low a sound is, which will be determined by the vibrations that created that sound.

primate: The order of mammals that includes humans, apes, monkeys and related animals (such as tarsiers, the Daubentonia and other lemurs).

range: The full extent or distribution of something. For instance, a plant or animal’s range is the area over which it naturally exists.

reptile: Vertebrate animals belonging to a group known as Reptilia. Most reptiles have skin that is covered with scales or horny plates. Snakes, turtles, lizards and alligators are all reptiles. Once considered their own separate group, birds now belong to this order. With the exception of modern birds, most modern reptiles are cold-blooded (or ectothermic).

respiratory tract: Parts of the body involved in breathing (also called the respiratory system). It includes the lungs, nose, sinuses, throat and other large airways.

rodent: A mammal of the order Rodentia, a group that includes mice, rats, squirrels, guinea pigs, hamsters and porcupines.

social: (adj.) Relating to gatherings of people; a term for animals (or people) that prefer to exist in groups. (noun) A gathering of people, for instance those who belong to a club or other organization, for the purpose of enjoying each other’s company.

society: An integrated group of people or animals that generally cooperate and support one another for the greater good of them all.

species: A group of similar organisms capable of producing offspring that can survive and reproduce.

system: A network of parts that together work to achieve some function. For instance, the blood, vessels and heart are primary components of the human body's circulatory system. Similarly, trains, platforms, tracks, roadway signals and overpasses are among the potential components of a nation's railway system. System can even be applied to the processes or ideas that are part of some method or ordered set of procedures for getting a task done.

tone: (in acoustics) The pitch of a sound, especially for musical notes.

tract: A particular, well-defined area. It can be a patch of land, such as the area on which a house is located. Or it can be a bit of real estate in the body. For instance, important parts of an animal’s body will include its respiratory tract (lungs and airways), reproductive tract (gonads and hormone systems important to reproduction) and gastro-intestinal tract (the stomach and intestines — or organs responsible for moving food, digesting it, absorbing it and eliminating wastes).

unique: Something that is unlike anything else; the only one of its kind.

valve: Something that can reduce or shut off the flow of some gas or liquid through a pipe or other passageway. Some specialized valves may allow a liquid or gas to flow in one direction only.

voice box: The hollow, muscular organ forming an air passage to the lungs and holding the vocal cords in people and other mammals. It’s also known as the larynx.

About Jake Buehler

Jake Buehler is a freelance science writer, covering natural history, wildlife conservation and Earth's splendid biodiversity, from salamanders to sequoias. He has a master's degree in zoology from the University of Hawaii at Manoa.

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