Donald Trump tore into four Republican senators who oppose his intentions to impose sweeping tariffs on Wednesday.

The president urged Kentucky Sens. Mitch McConnell and Rand Paul, as well as Maine Sen. Susan Collins and Alaska Sen. Lisa Murkowski to get on board with his tariff proposal.

Trump claimed in a post to his Truth Social account that these four senators are responsible for 'allowing fentanyl to pour into our country unchecked' and he warned them against voting with a Democrat bill aimed at stopping the new tariffs on Canada.

'What's wrong with them,' he questioned, claiming the four are 'suffering from Trump Derangement Syndrome.'

On Wednesday afternoon, Trump is holding the first Rose Garden event of his second term for his so-called 'Liberation Day' as part of his 'Make America Wealthy Again' agenda. 

He will announce a slew of new tariffs in a push to encourage bringing industry back to the U.S. rather than outsourcing to other countries. The tariffs, Trump says, are also aimed at punishing other nations for contributing to the proliferation of the fentanyl crisis in the U.S.

'The Senate Bill is just a ploy of the Dems to show and expose the weakness of certain Republicans, namely these four,' Trump claimed. '[I]t is not going anywhere because the House will never approve it and I, as your President, will never sign it.'

Just hours before Trump prepares for the announcement of new tariffs on Wednesday, he took to his social media to tell his supporters in Kentucky, Maine and Alaska to reach out to their senators to urge them to support tariffs for Canada.

Trump and his allies have often referred to more moderate Republicans or those who ever break with the party as a 'RINO' or Republican in Name Only.

While he didn't use that term in the post on Wednesday, the president did allude to the fact that these four Republican senators are traitors who will face backlash if they vote to block his tariffs.

'They have been extremely difficult to deal with and, unbelievably disloyal to hardworking Majority Leader John Thune, and the Republican Party itself,' Trump said.

Trump says that Canada, specifically, must face the fallout of the fentanyl crisis.

He plans to implement on Wednesday a slew of retaliatory tariffs – including on the European Union, a top US ally; on Russia, over the war in Ukraine; on any country that buys fuel from Venezuela; and on BRICs nations, for wanting to develop a currency to compete with the US dollar.